A toxicity test that establishes the concentration at which a specific endpoint occurs is called?

A toxicity test that establishes the concentration at which a specific endpoint occurs is best described as a definitive test. This type of test is designed to provide quantitative data regarding the effects of a substance at varying concentrations, allowing for precise determination of toxicity levels along with clear identification of dosage-response relationships.

Definitive tests typically involve controlled conditions and are intended to confirm specific doses and their corresponding impacts on organisms or biological systems. By doing so, they help inform regulatory decisions, risk assessments, and safety evaluations.

In contrast, the other types of tests do not focus specifically on establishing a definitive concentration-response endpoint. Static tests, while they may assess toxicity, do not necessarily define an endpoint concentration. Screening tests are often used to identify potential toxicity without providing detailed quantitative data. Validation tests aim to ensure that an assay or procedure is accurate and reliable, rather than focusing on definitive concentration data.